Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545207 | 1.00 | GAA (0.34) | GAAL3MBTL1GFERPOLBKDM4E | |
| SCHEMBL11207393 | 0.83 | GAA (0.38) | GAAL3MBTL1POLB | |
| SCHEMBL10545712 | 0.83 | GAA (0.34) | GAAL3MBTL1POLB | |
| SCHEMBL11202737 | 0.82 | GAA (0.37) | GAAL3MBTL1POLB | |
| SCHEMBL11211147 | 0.82 | GAA (0.34) | GAAL3MBTL1POLB | |
| SCHEMBL10546548 | 0.81 | GAA (0.34) | GAAL3MBTL1GFERPOLB | |
| SCHEMBL10810781 | 0.81 | GAA (0.34) | GAAL3MBTL1GFERPOLB | |
| SCHEMBL11209045 | 0.79 | GAA (0.35) | GAAL3MBTL1POLB | |
| SCHEMBL11205996 | 0.79 | GAA (0.38) | GAAL3MBTL1POLB | |
| SCHEMBL10361567 | 0.78 | GAA (0.40) | GAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095764-B1 | 2-OXOAZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
| EP-0053815-B1 | 2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |
| EP-0021676-B1 | 3-METHOXY-2-OXOAZETIDINE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1983-09-14 | — | — | EP | disclosed |