Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202737 | 0.83 | GAA (0.37) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10545712 | 0.81 | GAA (0.34) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10545798 | 0.81 | GAA (0.34) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10810790 | 0.79 | GAA (0.34) | GAAL3MBTL1POLB | |
| SCHEMBL10545207 | 0.79 | GAA (0.34) | GAAL3MBTL1POLB | |
| SCHEMBL9659481 | 0.79 | GAA (0.40) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10361567 | 0.79 | GAA (0.40) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL11211147 | 0.78 | GAA (0.34) | GAAL3MBTL1POLBHDAC1HDAC2 | |
| SCHEMBL10729925 | 0.77 | CAPN1 (0.47) | — | |
| SCHEMBL9328985 | 0.75 | GAA (0.37) | GAAL3MBTL1POLBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095764-A2 | 2-Oxoazetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |
| EP-0021676-A1 | 3-Methoxy-2-oxoazetidine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |