Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | UTRN | P46939 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10813153 | 1.00 | KDM4E (0.45) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10808691 | 0.85 | EGFR (0.41) | KDM4EELANEKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10808687 | 0.85 | EGFR (0.41) | KDM4EELANEKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4467298 | 0.85 | KDM4E (0.58) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10814152 | 0.85 | ELANE (0.42) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL4467304 | 0.85 | KDM4E (0.58) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10814157 | 0.85 | ELANE (0.42) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10808484 | 0.81 | ELANE (0.44) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10808490 | 0.81 | ELANE (0.44) | KDM4EELANEKMT2AUTRNNPC1 | |
| SCHEMBL10818729 | 0.80 | KDM4E (0.44) | KDM4EELANEKMT2AUTRNNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | disclosed |