Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467298 | 1.00 | KDM4E (0.58) | KDM4EELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10813700 | 0.87 | KDM4E (0.48) | KDM4ENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10813695 | 0.87 | KDM4E (0.48) | KDM4ENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10810334 | 0.86 | KDM4E (0.47) | KDM4ENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10810340 | 0.86 | KDM4E (0.47) | KDM4ENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10813153 | 0.85 | KDM4E (0.45) | KDM4EELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10813151 | 0.85 | KDM4E (0.45) | KDM4EELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10818727 | 0.83 | KDM4E (0.44) | KDM4EELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10818729 | 0.83 | KDM4E (0.44) | KDM4EELANENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10809388 | 0.83 | NPC1 (0.46) | KDM4EELANENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | claimed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | claimed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | claimed |
| JP-58219169-A | — | — | None | — | — | JP | disclosed |
| US-7557123-B2 | Heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1403253-A1 | NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| CN-1471517-A | OXAZOLYL-arylpropionic acid derivatives and their sue as PPAR agonists | — | 2004-01-28 | — | — | CN | disclosed |
| EP-0603419-A1 | NOVEL THIAZOLIDINEDIONE COMPOUND AND USE THEREOF | Japan Tobacco Inc. (JP) | 1994-06-29 | — | — | EP | disclosed |
| EP-0096890-B1 | OXAZOLEACETIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING SAID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4602027-A | HYPOGLYCEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| EP-0096890-A2 | Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives | Takeda Chemical Industries, Ltd. (JP) | 1983-12-28 | — | — | EP | disclosed |
| JP-S58219169-A | OXAZOLEACETIC ACID DERIVATIVE | TAKEDA CHEM IND LTD | 1983-12-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | GPR119, INSR, GLP1R | KDM4E 1075/4885ELANE 4695/4885NPC1 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.