Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635204 | 0.88 | PPARG (0.56) | SMN1; SMN2LMNAALDH1A1HTTNCOA1 | |
| SCHEMBL14087052 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL11841853 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAMMP8MDM4MAPT | |
| SCHEMBL24661545 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAHTTMMP8MDM4 | |
| SCHEMBL21275416 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2LMNAALDH1A1MMP8MDM4 | |
| SCHEMBL28510565 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAMMP8MDM4MAPT | |
| SCHEMBL27813948 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2LMNAALDH1A1HTTNCOA1 | |
| SCHEMBL28300956 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2LMNAALDH1A1HTTNCOA1 | |
| SCHEMBL11127543 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2LMNAALDH1A1HTTNCOA1 | |
| SCHEMBL3923931 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1MMP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716156-A | INSECTICIDES, MITICIDES | STAUFFER CHEMICAL CO. (US) | 1987-12-29 | — | — | US | disclosed |
| US-4385922-A | Method of increasing the yield of legumes utilizing D- or DL-α-O,O-diethlyphosphorodithioylacetylphenylglycine ethyl esters | STAUFFER CHEMICAL COMPANY (US) | 1983-05-31 | — | — | US | disclosed |