Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057057 | 0.89 | CYP3A4 (0.59) | OGG1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL9665470 | 0.83 | OGG1 (0.61) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10917880 | 0.83 | OGG1 (0.61) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10916395 | 0.83 | OGG1 (0.61) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11119666 | 0.83 | CYP3A4 (0.52) | OGG1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL8757356 | 0.82 | CYP3A4 (0.49) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11372412 | 0.82 | OGG1 (0.60) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10916378 | 0.82 | OGG1 (0.60) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10916373 | 0.82 | OGG1 (0.60) | OGG1CYP27B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9308406 | 0.82 | CYP3A4 (0.51) | OGG1CYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126581-B1 | ANTIFUNGAL TRIAZOLE DERIVATIVES | Pfizer Limited (GB) | 1987-06-03 | — | — | EP | disclosed |
| EP-0044605-B1 | FUNGICIDAL BIS-AZOLYL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-02-12 | — | — | EP | disclosed |
| US-4554286-A | Antifungal 1-triazolyl-2-aryl-3-(5-trifluoromethylimidazol-1-yl)propan-2-ol derivatives | PFIZER INC. (US) | 1985-11-19 | — | — | US | disclosed |
| US-4523019-A | INTERMEDIATE FOR FUNGICIDE AND PLANT GROWTH REGULATOR | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-11 | — | — | US | disclosed |
| EP-0126581-A1 | Antifungal triazole derivatives | Pfizer Limited (GB) | 1984-11-28 | — | — | EP | disclosed |
| EP-0111658-A2 | 1,3-Dihalopropan-2-ols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-27 | — | — | EP | disclosed |
| US-4416682-A | 1,3-Bis(azolyl)propanols as fungicides and plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-22 | — | — | US | disclosed |
| EP-0044605-A1 | Fungicidal bis-azolyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |