Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815783 | 0.78 | MEN1 (0.50) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL10813769 | 0.74 | KDM4E (0.46) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL10816529 | 0.72 | NPSR1 (0.51) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL8018580 | 0.68 | KDM4E (0.65) | KDM4ESMN1; SMN2LMNAHIF1ANPC1 | |
| SCHEMBL26242534 | 0.68 | KDM4E (0.50) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL7546814 | 0.68 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL11191361 | 0.68 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL5590833 | 0.66 | TP53 (0.65) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL20348127 | 0.66 | KDM4E (0.51) | KDM4ESMN1; SMN2LMNAHIF1AMITF | |
| SCHEMBL20371378 | 0.66 | KDM4E (0.59) | KDM4ESMN1; SMN2LMNAHIF1AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077983-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4616014-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0077983-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-04 | — | — | EP | disclosed |