Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329851 | 0.86 | TSHR (0.57) | CYP2C19CYP1A2TSHRLOXL2MAPK1 | |
| SCHEMBL43494 | 0.84 | CYP2C19 (0.57) | CYP2C19CYP1A2TSHRLOXL2MAPK1 | |
| SCHEMBL30643815 | 0.82 | CYP2C19 (0.64) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL76204 | 0.82 | CYP2C19 (0.64) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| Ethylene SCHEMBL11190134 | 0.81 | CYP2C19 (0.54) | CYP2C19CYP1A2TSHRLOXL2MAPK1 | |
| SCHEMBL1369959 | 0.80 | CYP2C19 (0.62) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL3267307 | 0.80 | CYP2C19 (0.57) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL27861234 | 0.80 | CYP2C19 (0.62) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| SCHEMBL5160372 | 0.80 | CYP2C19 (0.67) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2527458 | 0.80 | CYP2C19 (0.62) | CYP2C19CYP1A2TSHRLOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130025-B1 | 2-ALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4619924-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0130025-A1 | 2-Alkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-02 | — | — | EP | disclosed |