Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11190134 | 0.96 | CYP2C19 (0.54) | CYP2C19CYP1A2MAPK1TSHRMAPT | |
| SCHEMBL4617406 | 0.91 | ALDH1A1 (0.60) | CYP2C19CYP1A2MAPK1MAPTGAA | |
| SCHEMBL7329851 | 0.86 | TSHR (0.57) | CYP2C19CYP1A2MAPK1TSHRMAPT | |
| SCHEMBL10815212 | 0.84 | CYP2C19 (0.57) | CYP2C19CYP1A2MAPK1TSHRMAPT | |
| SCHEMBL6932662 | 0.83 | CYP2C19 (0.61) | CYP2C19CYP1A2TSHRMAPTGAA | |
| Silver SCHEMBL11309103 | 0.82 | CYP2C19 (0.59) | CYP2C19CYP1A2TSHRMAPTGAA | |
| SCHEMBL30643815 | 0.82 | CYP2C19 (0.64) | CYP2C19CYP1A2TSHRMAPTGAA | |
| SCHEMBL1369962 | 0.82 | CYP2C19 (0.59) | CYP2C19CYP1A2TSHRMAPTGAA | |
| SCHEMBL76204 | 0.82 | CYP2C19 (0.64) | CYP2C19CYP1A2TSHRMAPTGAA | |
| SCHEMBL3089874 | 0.82 | CYP2C19 (0.59) | CYP2C19CYP1A2TSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250033082-A1 | METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS | ADAMA MAKHTESHIM LTD. (IL) | 2025-01-30 | — | — | US | claimed |
| EP-4423178-A1 | METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS | ADAMA MAKHTESHIM LTD. (IL) | 2024-09-04 | — | — | EP | claimed |
| CN-118201991-A | Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor | 安道麦马克西姆有限公司 | 2024-06-14 | — | — | CN | claimed |
| WO-2023073536-A1 | METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS | ADAMA MAKHTESHIM LTD. (IL) | 2023-05-04 | — | — | WO | claimed |
| CN-114031502-A | Preparation method of p-nitroacetophenone | 南京一苇医药科技有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-110590529-A | Preparation method of 1-aryl-2-acetone compound | 浙江医药高等专科学校 | 2019-12-20 | — | — | CN | claimed |
| CN-109705051-A | Tri- substituted oxazoline of 2,4,5- and its synthetic method | 湖南城市学院 | 2019-05-03 | — | — | CN | claimed |
| CN-104177298-B | Bis- substitution -4,5- dihydros -1H of 4,4--imidazoles -5- ketone, derivative and its synthetic method | 湘潭大学 | 2018-10-02 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| CN-104177298-A | 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and derivatives thereof as well as synthesis method thereof | UNIV XIANGTAN | 2014-12-03 | — | — | CN | claimed |
| EP-4004001-B1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2025-09-03 | — | — | EP | disclosed |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners (US) | 2025-04-01 | — | — | US | disclosed |
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| US-20250033082-A1 | METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS | ADAMA MAKHTESHIM LTD. (IL) | 2025-01-30 | — | — | US | disclosed |
| US-20240368001-A1 | SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF | AQUAFORTUS TECHNOLOGIES LIMITED (NZ) | 2024-11-07 | — | — | US | disclosed |
| US-4559352-A | 1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof | STERLING DRUG INC. (US) | 1985-12-17 | — | — | US | disclosed |
| US-4515797-A | 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof | STERLING DRUG INC. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4465686-A | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation | STERLING DRUG INC. (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0068669-A1 | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |
| EP-0061774-A2 | 3-Amino-5-(substituted)-2 (1H) pyridinones and 3-cyano compounds useful as cardiotonics and preparation thereof | STERLING DRUG INC. (US) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CYP2C19 1581/4885CYP1A2 848/4885MAPK1 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.