Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | RECQL | P46063 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TEK | Q02763 | 1/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740883 | 1.00 | PTGS1 (0.72) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL10740881 | 1.00 | PTGS1 (0.72) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL10814101 | 0.95 | PTGS1 (0.68) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL10814105 | 0.95 | PTGS1 (0.68) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL10735144 | 0.92 | KDM4E (0.64) | PTGS1KDM4ERECQLTDP1MEN1 | |
| SCHEMBL10735137 | 0.92 | KDM4E (0.64) | PTGS1KDM4ERECQLTDP1MEN1 | |
| SCHEMBL10741985 | 0.90 | PTGS1 (0.77) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL10741979 | 0.90 | PTGS1 (0.77) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| SCHEMBL11498677 | 0.87 | PTGS1 (0.84) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 | |
| Ticarcillin Cresyl SCHEMBL27673599 | 0.86 | PTGS1 (0.73) | PTGS1SMN1; SMN2KDM4ERECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084948-B1 | PENICILLIN DERIVATIVES | BEECHAM GROUP PLC (GB) | 1987-11-04 | — | — | EP | claimed |