Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815521 | 1.00 | ALDH1A1 (0.35) | ALDH1A1PKMTSHRL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL10810433 | 0.98 | ALDH1A1 (0.34) | ALDH1A1PKMTSHRL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL10813591 | 0.98 | ALDH1A1 (0.34) | ALDH1A1PKMTSHRL3MBTL1LMNA | |
| SCHEMBL10809397 | 0.78 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL10815382 | 0.74 | — | — | |
| SCHEMBL10812256 | 0.72 | — | — | |
| SCHEMBL18517072 | 0.62 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL4623781 | 0.60 | TDP1 (0.49) | ALDH1A1TSHRLMNA | |
| SCHEMBL11964484 | 0.60 | TDP1 (0.49) | ALDH1A1TSHRLMNA | |
| SCHEMBL4624003 | 0.60 | TDP1 (0.49) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4697020-A | Derivatives of 2,4-thiazolidinedione | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |