Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18563084 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1RECQLHPGDMAPTRAB9A | |
| SCHEMBL11757417 | 0.73 | ALDH1A1 (0.39) | ALDH1A1RECQLHPGD | |
| SCHEMBL1110848 | 0.72 | MEN1 (0.44) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL9255069 | 0.71 | — | — | |
| SCHEMBL10670214 | 0.69 | ALDH1A1 (0.46) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL12332577 | 0.66 | ALDH1A1 (0.44) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL8519330 | 0.66 | MEN1 (0.40) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL10815974 | 0.66 | CYP2C9 (0.55) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL11034458 | 0.65 | ALDH1A1 (0.54) | ALDH1A1RECQLHPGDMEN1KMT2A | |
| SCHEMBL9247800 | 0.64 | ALDH1A1 (0.50) | ALDH1A1RECQLHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144668-B1 | METHOD FOR THE PREPARATION OF 3,4,6-TRISUBSTITUTED 3-ALKYLTHIO-1,2,4-TRIAZIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1987-12-23 | — | — | EP | claimed |
| US-4544744-A | ALKYLATION WITH OXYGEN-CONTAINING ACID ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | claimed |
| JP-60112777-A | — | — | None | — | — | JP | disclosed |
| JP-59021672-A | — | — | None | — | — | JP | disclosed |
| EP-0144668-B1 | METHOD FOR THE PREPARATION OF 3,4,6-TRISUBSTITUTED 3-ALKYLTHIO-1,2,4-TRIAZIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1987-12-23 | — | — | EP | disclosed |
| US-4544744-A | ALKYLATION WITH OXYGEN-CONTAINING ACID ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| US-4544744-A | ALKYLATION WITH OXYGEN-CONTAINING ACID ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| US-4544744-A | ALKYLATION WITH OXYGEN-CONTAINING ACID ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| EP-0144668-A1 | Method for the preparation of 3,4,6-trisubstituted 3-alkylthio-1,2,4-triazin-5-one derivatives | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| JP-S60112777-A | MANUFACTURE OF 3,4,6-TRISUBSTITUTED 3-ALKYLTHIO-1,2, 4-TRIAZIN-5-ONE | BAYER AG | 1985-06-19 | — | — | JP | disclosed |
| JP-S5921672-A | 4-ALLYL-1,2,4-TRIAZIN-5(2H)-ONE-3-THIONE DERIVATIVE AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1984-02-03 | — | — | JP | disclosed |