Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965899 | 0.95 | MTNR1A (0.49) | MTNR1AALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL8520039 | 0.82 | MTNR1A (0.48) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10615952 | 0.73 | HTR2A (0.66) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11395020 | 0.72 | PRKCD (0.51) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11789092 | 0.72 | MTNR1A (0.47) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11053763 | 0.72 | MTNR1A (0.53) | MTNR1ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL30395273 | 0.72 | MTNR1A (0.54) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30395009 | 0.72 | MTNR1A (0.54) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29058373 | 0.72 | MTNR1A (0.54) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12307218 | 0.71 | HTR2A (0.64) | MTNR1AALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642331-A | CONTACTING WITH AMINE ANTIOXIDANT | THE B. F. GOODRICH COMPANY (US) | 1987-02-10 | — | — | US | disclosed |