Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100780 | 0.89 | RAB9A (0.56) | GSK3BTDP1MAPTMAPK1POLB | |
| SCHEMBL1699272 | 0.84 | MAPT (0.53) | GSK3BTDP1MAPTMAPK1POLB | |
| SCHEMBL6386431 | 0.84 | TDP1 (0.44) | GSK3BPIN1TDP1MAPTMAPK1 | |
| SCHEMBL29695587 | 0.84 | TDP1 (0.73) | GSK3BPIN1TDP1MAPTMAPK1 | |
| SCHEMBL13506718 | 0.82 | GSK3B (0.56) | GSK3BPIN1TDP1MAPTMAPK1 | |
| SCHEMBL10138757 | 0.82 | GSK3B (0.56) | GSK3BPIN1TDP1MAPTMAPK1 | |
| SCHEMBL10810189 | 0.82 | JAK2 (0.58) | GSK3BPIN1TDP1MAPTMAPK1 | |
| SCHEMBL1858862 | 0.81 | KMT2A (0.56) | TDP1MAPTMAPK1POLBALDH1A1 | |
| SCHEMBL1624745 | 0.80 | TDP1 (0.49) | GSK3BTDP1MAPTMAPK1POLB | |
| SCHEMBL31717653 | 0.79 | MAPK1 (0.78) | GSK3BPIN1TDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698430-A | ANTIDEPRESSANT | A. H. ROBINS COMPANY, INC. (US) | 1987-10-06 | — | — | US | disclosed |
| US-4558132-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0099614-A2 | Nitro, amino and aroylamino-N-phenylpyridinamines and their use in a process for preparing pyrido(1,4)benzodiazapines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-02-01 | — | — | EP | disclosed |