Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | LATS1 | O95835 | 3/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18879034 | 0.81 | SLC2A1 (0.56) | SLC2A1HTTPTK2L3MBTL1TGFBR1 | |
| SCHEMBL10803018 | 0.77 | SLC2A1 (0.52) | SLC2A1HTTPTK2MAPTPIM1 | |
| SCHEMBL10805400 | 0.76 | SLC2A1 (0.97) | SLC2A1HTTL3MBTL1MAPTPOLB | |
| SCHEMBL10840466 | 0.75 | SLC2A1 (0.70) | SLC2A1HTTL3MBTL1MAPTPOLB | |
| SCHEMBL10507503 | 0.74 | CYP2C19 (0.52) | SLC2A1HTTPTK2POLB | |
| SCHEMBL10805234 | 0.74 | SLC2A1 (0.74) | SLC2A1HTTL3MBTL1TGFBR1MAPT | |
| SCHEMBL10801863 | 0.74 | SLC2A1 (0.70) | SLC2A1HTTL3MBTL1MAPTPOLB | |
| SCHEMBL10804993 | 0.74 | SLC2A1 (0.49) | SLC2A1HTTPTK2 | |
| SCHEMBL20272422 | 0.73 | SLC2A1 (0.47) | SLC2A1HTTPTK2MAPTPOLB | |
| SCHEMBL10801118 | 0.73 | SLC2A1 (0.48) | SLC2A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |