Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 3/20 | 0.31 |
| ▸ | NCF1 | P14598 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803018 | 0.83 | SLC2A1 (0.52) | SLC2A1HTTPTK2KMT2ACYP2C19 | |
| SCHEMBL10846163 | 0.81 | TLR7 (0.57) | SLC2A1ESR1TLR7HTTCYP2C19 | |
| SCHEMBL10507503 | 0.79 | CYP2C19 (0.52) | SLC2A1HTTPTK2MEN1KMT2A | |
| SCHEMBL10506617 | 0.78 | SLC2A1 (0.48) | SLC2A1HTTPTK2MEN1KMT2A | |
| SCHEMBL10801118 | 0.78 | SLC2A1 (0.48) | SLC2A1HTTSMN1; SMN2CYP2C19NQO2 | |
| SCHEMBL18879034 | 0.78 | SLC2A1 (0.56) | SLC2A1HTTPTK2NQO2 | |
| SCHEMBL10507451 | 0.77 | SLC2A1 (0.47) | SLC2A1HTTPTK2CYP2C19NQO2 | |
| SCHEMBL10506904 | 0.77 | NCF1 (0.56) | SLC2A1MEN1KMT2ACYP2C19NQO2 | |
| SCHEMBL10507638 | 0.77 | SLC2A1 (0.47) | SLC2A1MEN1KMT2ACYP2C19NQO2 | |
| SCHEMBL10805500 | 0.76 | SLC2A1 (0.49) | SLC2A1HTTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | claimed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | claimed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | disclosed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |