Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672916 | 0.93 | TP53 (0.41) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL1619512 | 0.87 | LMNA (0.50) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL10869368 | 0.86 | MEN1 (0.41) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL1619443 | 0.86 | SMN1; SMN2 (0.48) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL18672384 | 0.83 | LMNA (0.45) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL1619826 | 0.82 | LMNA (0.46) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL10496376 | 0.82 | LMNA (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL10695423 | 0.82 | TP53 (0.37) | TP53ADH1BADH1CADH1AADH4 | |
| SCHEMBL9949255 | 0.81 | SMN1; SMN2 (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1618292 | 0.81 | SMN1; SMN2 (0.44) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197985-A4 | COSMETIC COMPOSITIONS. | BAUSCH & LOMB (US) | 1987-02-19 | — | — | EP | disclosed |
| EP-0197985-A1 | COSMETIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 1986-10-22 | — | — | EP | disclosed |
| WO-1986002001-A1 | COSMETIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 1986-04-10 | — | — | WO | disclosed |