Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGFR | P43088 | 7/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399395 | 1.00 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399393 | 1.00 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL1081893 | 1.00 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL1081889 | 1.00 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399394 | 1.00 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399186 | 0.97 | ABCB11 (0.69) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399185 | 0.97 | ABCB11 (0.69) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399184 | 0.97 | ABCB11 (0.69) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL10103993 | 0.95 | ABCB11 (0.65) | ABCB11AKR1C3PTGS1PTGFRPTGER3 | |
| SCHEMBL399252 | 0.95 | ABCB11 (0.67) | ABCB11AKR1C3PTGS1PTGFRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274279-A1 | NITRIC OXIDE DONATING PROSTAMIDES | Nicox S.A. (FR) | 2011-01-19 | — | — | EP | disclosed |