Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 19/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081901 | 0.81 | ADORA2B (0.65) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4402271 | 0.80 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1063582 | 0.78 | ADORA2B (0.72) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1065581 | 0.74 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1065066 | 0.73 | ADORA2B (0.73) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1081715 | 0.73 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1065065 | 0.72 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4402342 | 0.71 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1063501 | 0.70 | ADORA2B (0.71) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4406728 | 0.67 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268641-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | Advinus Therapeutics Pvt. Ltd. (IN) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118759-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT. LTD., (IN) | 2009-10-01 | — | — | WO | disclosed |