Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115918 | 0.95 | ADORA2A (0.68) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL8467559 | 0.83 | ADORA2A (0.60) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL2116000 | 0.82 | ADORA2A (0.64) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL10589823 | 0.81 | ADORA2A (0.61) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL4551803 | 0.81 | ADORA2A (0.91) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL23228230 | 0.80 | ADORA2A (0.88) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL28176129 | 0.80 | ADORA2A (0.88) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL28228476 | 0.80 | ADORA2A (0.88) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL21469779 | 0.80 | ADORA2A (0.88) | ADORA2ACYP1A2TSHRADORA1ADORA2B | |
| SCHEMBL1741560 | 0.80 | ADORA2A (0.88) | ADORA2ACYP1A2TSHRADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534255-B1 | PROCESSES FOR PREPARING 1,3-DIOXOLANE NUCLEOSIDES | PHARMASSET INC (US) | 2011-01-19 | — | — | EP | claimed |