Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | ADH4 | P08319 | 1/20 | 0.47 |
| ▸ | ADH7 | P40394 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13756017 | 1.00 | FAAH (0.51) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL13755901 | 0.95 | FAAH (0.50) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL10820669 | 0.95 | FAAH (0.50) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL13755917 | 0.94 | FAAH (0.46) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL13755989 | 0.94 | FAAH (0.46) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL10820638 | 0.94 | FAAH (0.46) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL13756141 | 0.94 | FAAH (0.46) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL13756014 | 0.94 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL10820707 | 0.94 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1ADH1B | |
| SCHEMBL10820677 | 0.94 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476756-A1 | Amine-containing lipids and uses thereof | Massachusetts Institute of Technology (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2009097332-A2 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |