Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855648 | 0.82 | CA2 (0.36) | CA2GAAPOLBMAPK1NPSR1 | |
| SCHEMBL12855649 | 0.82 | CA2 (0.36) | CA2GAAPOLBMAPK1NPSR1 | |
| SCHEMBL10618642 | 0.80 | CA2 (0.42) | CA2GAAPABPC1CTDSP1 | |
| SCHEMBL328617 | 0.80 | CA2 (0.35) | CA2 | |
| SCHEMBL12855647 | 0.80 | CA2 (0.35) | CA2 | |
| SCHEMBL13191149 | 0.80 | CA2 (0.39) | CA2GAAPABPC1CTDSP1 | |
| SCHEMBL21549585 | 0.79 | CA2 (0.36) | CA2GAAPOLBMAPK1NPSR1 | |
| SCHEMBL2757759 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL2757779 | 0.78 | CA2 (0.36) | CA2GAAPABPC1CTDSP1 | |
| SCHEMBL16382539 | 0.78 | CA2 (0.36) | CA2GAAPABPC1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | claimed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | claimed |