Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822459 | 0.90 | NPC1 (0.53) | NPC1NQO1RECQLALDH1A1ADORA2A | |
| SCHEMBL10822556 | 0.90 | IDO1 (0.55) | NPC1NQO1IDO1RECQLEP300 | |
| SCHEMBL10486300 | 0.74 | NPC1 (0.71) | NPC1ALDH1A1ADORA2AMAPTMEN1 | |
| SCHEMBL16117351 | 0.72 | IDO1 (0.47) | NQO1IDO1EP300KAT8ALDH1A1 | |
| SCHEMBL3678540 | 0.72 | HSP90AA1 (0.58) | NPC1RECQLALDH1A1ADORA2ALMNA | |
| SCHEMBL10822471 | 0.72 | MAPT (0.66) | NQO1IDO1EP300KAT8ALDH1A1 | |
| SCHEMBL10822990 | 0.72 | NPC1 (0.46) | NPC1ALDH1A1ADORA2AMAPTMEN1 | |
| SCHEMBL6031052 | 0.71 | MAPT (0.48) | NQO1IDO1EP300KAT8ALDH1A1 | |
| SCHEMBL30620880 | 0.71 | MAPT (0.48) | NQO1IDO1EP300KAT8ALDH1A1 | |
| SCHEMBL30416160 | 0.71 | MAPT (0.48) | NQO1IDO1EP300KAT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |