Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822820 | 0.90 | NPC1 (0.48) | NPC1TLR8RECQLALDH1A1HSP90AA1 | |
| SCHEMBL3678540 | 0.80 | HSP90AA1 (0.58) | NPC1RECQLALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL10486300 | 0.79 | NPC1 (0.71) | NPC1ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2 | |
| SCHEMBL28232454 | 0.79 | NQO1 (0.60) | TLR8ALDH1A1SMN1; SMN2NQO1HPGD | |
| SCHEMBL10822527 | 0.76 | SMN1; SMN2 (0.51) | NPC1SMN1; SMN2HTTRAB9A | |
| SCHEMBL10822556 | 0.76 | IDO1 (0.55) | NPC1RECQLALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL10344664 | 0.76 | ALDH1A1 (0.41) | NPC1TLR8RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL9566435 | 0.75 | MGAM (0.54) | NPC1RECQLALDH1A1AGPAT2SMN1; SMN2 | |
| SCHEMBL9566471 | 0.75 | RECQL (0.78) | RECQLALDH1A1HSP90AA1HSP90AB1AGPAT2 | |
| SCHEMBL6668063 | 0.74 | NPC1 (0.55) | NPC1RECQLALDH1A1AGPAT2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | claimed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | claimed |
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |