Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818132 | 0.87 | PTGDR2 (0.62) | KDM4EPTGDR2ALDH1A1HPGDALOX5 | |
| SCHEMBL27607932 | 0.80 | RAB9A (0.50) | KDM4EPTGDR2ALDH1A1ALOX5MAPT | |
| SCHEMBL29011402 | 0.78 | PTGDR2 (0.48) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL12608906 | 0.76 | PTGDR2 (0.81) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL4485015 | 0.76 | CDC7 (0.71) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL28056053 | 0.75 | RAB9A (0.46) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11097519 | 0.74 | PTGDR2 (0.79) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL2821292 | 0.74 | ABL1 (0.41) | PTGDR2ALOX5MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2760388 | 0.74 | APEX1 (0.72) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL11456645 | 0.74 | APEX1 (0.72) | KDM4EPTGDR2ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276729-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2011-01-26 | — | — | EP | claimed |
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | claimed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | claimed |
| CN-1747731-A | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders | ALTANA PHARMA AG (DE) | 2006-03-15 | — | — | CN | claimed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| CN-103772259-B | There is positively charged aryl and the heteroaryl acetic acid class prodrug of rapid skin penetration speed | 于崇曦 | 2016-08-31 | — | — | CN | disclosed |
| CN-103772259-A | Positively charged aryl and heteroaryl acetic acid prodrugs with fast skin penetration rates | YU CHONGXI | 2014-05-07 | — | — | CN | disclosed |
| CN-103772258-A | Positively charged aryl and heteroaryl acetic acid prodrugs with fast skin penetration rates | YU CHONGXI | 2014-05-07 | — | — | CN | disclosed |
| CN-102307857-A | High penetration compositions and their use | CHONGXI YU | 2012-01-04 | — | — | CN | disclosed |
| CN-101506160-A | Positively charged aryl and heteroaryl acetic acid prodrugs with fast skin penetration rates | CHONGXI YU (US) | 2009-08-12 | — | — | CN | disclosed |
| CN-100496607-C | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2009-06-10 | — | — | CN | disclosed |
| CN-1747731-A | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders | ALTANA PHARMA AG (DE) | 2006-03-15 | — | — | CN | disclosed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | disclosed |