Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.68 |
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL108475 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1010631 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL6664068 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL3163862 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL21958268 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL10898181 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL9253149 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1008761 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL20704875 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1535444 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206374-B | High-density polyethylene material and application thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-102153806-B | Plastic filling master batch and preparation method thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-103122108-A | Processing assistant for polyvinyl chloride (PVC) and preparation method thereof | JIANGSU ATE POLYMER MATERIALS CO LTD | 2013-05-29 | — | — | CN | disclosed |
| CN-102212206-A | White carbon black filler and preparation method thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-102206374-A | High-density polyethylene material and application thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2011-10-05 | — | — | CN | disclosed |
| CN-102153806-A | Plastic filling master batch and preparation method thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2011-08-17 | — | — | CN | disclosed |
| EP-0120618-B1 | GLUE STICK ADHESIVES | BOSTIK LIMITED (GB) | 1986-10-22 | — | — | EP | disclosed |
| US-4618643-A | THERMOPLASTIC COPOLYESTER | USM CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0120618-A1 | Glue stick adhesives | BOSTIK LIMITED (GB) | 1984-10-03 | — | — | EP | disclosed |