Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3 | P19429 | 1/20 | 0.51 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.51 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823519 | 0.88 | IDH1 (0.49) | IDH1PKMPRMT1CA1CA2 | |
| SCHEMBL10823428 | 0.88 | TNNI3 (0.49) | TNNI3TNNT2TNNC1HKDC1PKM | |
| SCHEMBL10823613 | 0.85 | PRMT1 (0.49) | IDH1PKMPRMT1 | |
| SCHEMBL10823567 | 0.85 | IDH1 (0.48) | IDH1PKMPRMT1CA1CA2 | |
| SCHEMBL10629458 | 0.85 | TNNI3 (0.58) | TNNI3TNNT2TNNC1HKDC1PRMT1 | |
| SCHEMBL10823710 | 0.83 | MEN1 (0.50) | IDH1PKMPRMT1MEN1KMT2A | |
| SCHEMBL10823355 | 0.83 | IDH1 (0.48) | IDH1PKMPRMT1MAPTMEN1 | |
| SCHEMBL10823720 | 0.83 | MAPT (0.47) | IDH1PKMPRMT1CA1CA2 | |
| SCHEMBL10823476 | 0.83 | PRMT1 (0.62) | PKMPRMT1MEN1KMT2A | |
| SCHEMBL10823421 | 0.82 | MEN1 (0.48) | IDH1PKMPRMT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |