Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IDH1 | O75874 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823450 | 0.88 | CA2 (0.49) | MEN1KMT2AALDH1A1PRMT1 | |
| SCHEMBL6078231 | 0.86 | MEN1 (0.56) | MEN1KMT2AIDH1AKR1C3PKM | |
| SCHEMBL6079410 | 0.84 | MEN1 (0.55) | MEN1KMT2AIDH1AKR1C3PKM | |
| SCHEMBL6078878 | 0.84 | MEN1 (0.55) | MEN1KMT2AIDH1AKR1C3PKM | |
| SCHEMBL6078621 | 0.84 | MEN1 (0.55) | MEN1KMT2AIDH1AKR1C3PKM | |
| SCHEMBL6079569 | 0.84 | MEN1 (0.55) | MEN1KMT2AIDH1AKR1C3PKM | |
| SCHEMBL10823476 | 0.84 | PRMT1 (0.62) | MEN1KMT2APKMPRMT1 | |
| SCHEMBL10823613 | 0.84 | PRMT1 (0.49) | IDH1AKR1C3PKMPRMT1 | |
| SCHEMBL7630246 | 0.84 | MEN1 (0.62) | MEN1KMT2AAKR1C3PKMALDH1A1 | |
| SCHEMBL6079560 | 0.83 | MEN1 (0.54) | MEN1KMT2AIDH1AKR1C3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |