Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823698 | 0.91 | PRMT1 (0.55) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823723 | 0.90 | PRMT1 (0.52) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823416 | 0.85 | MEN1 (0.49) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823762 | 0.83 | EP300 (0.46) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823476 | 0.83 | PRMT1 (0.62) | PRMT1MEN1KMT2ANT5E | |
| SCHEMBL10823435 | 0.83 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823537 | 0.83 | PRMT1 (0.52) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6078800 | 0.81 | PRMT1 (0.74) | PRMT1MAPTCA12CA1CA2 | |
| SCHEMBL11341928 | 0.81 | TIMP3 (0.63) | PRMT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823442 | 0.81 | MEN1 (0.49) | PRMT1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |