Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823346 | 0.88 | CHEK1 (0.45) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL10823419 | 0.88 | MAPT (0.51) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823689 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823717 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823562 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823701 | 0.83 | MEN1 (0.48) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823561 | 0.83 | PRMT1 (0.51) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823442 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823438 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL10823508 | 0.81 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |