Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 2/20 | 0.43 |
| ▸ | CD40LG | P29965 | 2/20 | 0.43 |
| ▸ | UQCRB | P14927 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823482 | 0.88 | MEN1 (0.49) | LMNAMEN1KMT2AHTTTTR | |
| SCHEMBL10823418 | 0.87 | UQCRB (0.47) | LMNAMEN1KMT2AHTTTDP1 | |
| SCHEMBL10823453 | 0.85 | LMNA (0.46) | LMNAMEN1KMT2AHTTCD40 | |
| SCHEMBL10823770 | 0.83 | HKDC1 (0.50) | LMNAMEN1KMT2AHTTUQCRB | |
| SCHEMBL10823431 | 0.83 | CHEK1 (0.45) | CHEK1CDK8NEK2LIMK1LMNA | |
| SCHEMBL10823726 | 0.82 | PSD (0.49) | LMNAMEN1KMT2AHTTTDP1 | |
| SCHEMBL11342795 | 0.82 | CD40 (0.58) | MEN1KMT2ATTRFABP4CCNA2 | |
| SCHEMBL10823384 | 0.80 | LMNA (0.46) | LMNAMEN1KMT2AHTTUQCRB | |
| SCHEMBL10823703 | 0.80 | PRMT1 (0.55) | CHEK1CDK8NEK2LIMK1LMNA | |
| SCHEMBL10823759 | 0.79 | MEN1 (0.46) | LMNAMEN1KMT2AHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |