Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | UQCRB | P14927 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823595 | 0.85 | UQCRB (0.41) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823759 | 0.85 | MEN1 (0.46) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL10823454 | 0.84 | CA12 (0.41) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823439 | 0.84 | APEX1 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823747 | 0.84 | MAPT (0.51) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11344815 | 0.82 | MEN1 (0.49) | MEN1KMT2AHPSEPOLBALDH1A1 | |
| SCHEMBL10823534 | 0.81 | CA12 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823477 | 0.81 | CA12 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10823624 | 0.81 | IDH1 (0.53) | IDH2 | |
| SCHEMBL10823417 | 0.80 | EP300 (0.46) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |