UQCRB — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL808375	0.61	4/20
SCHEMBL3259826	0.73	3/20
SCHEMBL1592342	0.72	3/20
SCHEMBL208685	0.67	3/20
SCHEMBL3658163	0.59	3/20
SCHEMBL5202188	0.58	3/20
SCHEMBL2840272	0.56	3/20
SCHEMBL4930867	0.56	3/20
SCHEMBL2157586	0.55	3/20
SCHEMBL419881	0.54	3/20
SCHEMBL2308475	0.54	3/20
SCHEMBL2748031	0.53	3/20
SCHEMBL3994870	0.51	3/20
SCHEMBL209645	0.51	3/20
SCHEMBL3951985	0.51	3/20
SCHEMBL2748545	0.49	3/20
SCHEMBL3947998	0.48	3/20
SCHEMBL383925	0.42	3/20
SCHEMBL812679	0.83	2/20
SCHEMBL523563	0.80	2/20

Clinical trials — most relevant to UQCRB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Evaluation of the Effects of Calcitriol's in the Neurological Symptoms of Friedreich's Ataxia Patients	PHASE4	COMPLETED
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases	PHASE3	RECRUITING
Prevent Cardiac Surgery Associated AKI Trial	PHASE2	RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Effects of Chronic Dietary Exposure to Branched Chain Amino Acids	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Mitochondrial Assessment in Critical Ill Patients in Intensive Care	nan	NOT_YET_RECRUITING
Choroid Plexus Dysfunction in Neurological Diseases	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Transcranial Photobiomodulation for the Treatment of Pediatric Depression	nan	WITHDRAWN
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy	nan	RECRUITING
Ultrastructural Characteristics of Mitochondria in Cardiomyocytes in Heart Failure	nan	RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Mitoquines in COPD	nan	UNKNOWN
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers	nan	UNKNOWN
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a UQCRB binder may also engage these)

Protein	Name	Similarity
Q5RC24	—	1.000	Q5RC24 →
P00129	—	1.000	P00129 →
Q9D855	—	1.000	Q9D855 →
A0A0K2GUJ4	—	0.992	A0A0K2GUJ4 →
Q871K1	—	0.991	Q871K1 →
M9RZ95	—	0.990	M9RZ95 →
Q6C3K7	—	0.989	Q6C3K7 →
Q5BJJ8	—	0.987	Q5BJJ8 →
P90993	—	0.987	P90993 →
Q66KZ3	—	0.986	Q66KZ3 →
P34621	—	0.986	P34621 →
Q94K18	—	0.985	Q94K18 →
O74533	—	0.985	O74533 →
Q6CAD1	—	0.984	Q6CAD1 →
Q02378	—	0.984	Q02378 →
C4XVW1	—	0.984	C4XVW1 →
Q6FSJ2	—	0.984	Q6FSJ2 →
O60169	—	0.984	O60169 →
Q9D2R8	—	0.984	Q9D2R8 →
A7EF41	—	0.983	A7EF41 →
Q02950	—	0.983	Q02950 →
Q61SE7	—	0.983	Q61SE7 →
A0A1D8PJ73	—	0.983	A0A1D8PJ73 →
Q9GP40	—	0.983	Q9GP40 →
Q29PG4	—	0.983	Q29PG4 →
Q61Z75	—	0.983	Q61Z75 →
P53305	—	0.983	P53305 →
Q17439	—	0.983	Q17439 →
Q6PBR7	—	0.982	Q6PBR7 →
P0DN35	—	0.982	P0DN35 →