Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.63 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.63 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.63 |
| ▸ | SCN1A | P35498 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281664 | 0.92 | CACNA1C (0.68) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10823911 | 0.90 | CACNA1C (0.78) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL11831647 | 0.90 | CACNA1C (0.66) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10748959 | 0.90 | CACNA1C (0.66) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10823942 | 0.90 | CACNA1D (0.65) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10747212 | 0.89 | CACNA1D (0.64) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10823902 | 0.89 | ADORA3 (0.77) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL8093521 | 0.89 | CYP1A2 (0.75) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL11199582 | 0.87 | CACNA1C (0.61) | CACNA1CLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10823907 | 0.86 | CACNA1C (0.59) | CACNA1CLMNACACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565824-A | Certain nitratoalkyl ester dihydropyridines having antihypertensive properties | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |