Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27658785 | 0.98 | TOP1 (0.39) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL2781234 | 0.85 | TOP1 (0.38) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL17177392 | 0.83 | TOP1 (0.41) | TOP1PTGS1PTGS2TGFBR1 | |
| SCHEMBL30019890 | 0.82 | TOP1 (0.41) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| Guaiacol SCHEMBL27727259 | 0.81 | TP53 (0.47) | ALDH1A1HSD17B10TSHRMAPTKDM4E | |
| SCHEMBL2083077 | 0.80 | ALDH1A1 (0.42) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL819947 | 0.78 | KDM4E (0.48) | ALDH1A1HSD17B10HTTMAPTKDM4E | |
| SCHEMBL9000310 | 0.78 | TOP1 (0.42) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL5507245 | 0.77 | CYP11B1 (0.46) | TOP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL554430 | 0.77 | LRRK2 (0.39) | ALDH1A1PTGS1PTGS2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102417925-A | Reagent for detecting potassium ion content in blood, preparation method and kit containing reagent | TIANJIN HEOWNS BIOTECHNOLOGY CO LTD | 2012-04-18 | — | — | CN | claimed |
| JP-61060651-A | — | — | None | — | — | JP | disclosed |
| CN-105906554-A | Acrylate styryl pyridinium salts as well as synthesis and application thereof | 湖北固润科技股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-103472239-A | Preparation method of creatinine content detection reagent with three-layer structure | TIANJIN HEOWNS BIOCHEM TECHNOLOGIES CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-103472041-A | Use method for creatinine content detection kit | TIANJIN HEOWNS BIOCHEM TECHNOLOGIES CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-102375066-B | Creatinine content detection reagent and kit, and preparation and use methods of kit | TIANJIN HEOWNS BIOTECHNOLOGY CO LTD | 2013-10-16 | — | — | CN | disclosed |
| CN-102417925-A | Reagent for detecting potassium ion content in blood, preparation method and kit containing reagent | TIANJIN HEOWNS BIOTECHNOLOGY CO LTD | 2012-04-18 | — | — | CN | disclosed |
| CN-102375066-A | Creatinine content detection reagent and kit, and preparation and use methods of kit | TIANJIN HEOWNS BIOTECHNOLOGY CO LTD | 2012-03-14 | — | — | CN | disclosed |
| CN-1237969-C | therapeutic agent for chronic articular rheumatism | NIPPON SHINYAKU CO LTD (JP) | 2006-01-25 | — | — | CN | disclosed |
| CN-1501801-A | therapeutic agent for chronic articular rheumatism | 日本新药株式会社 | 2004-06-02 | — | — | CN | disclosed |
| JP-S6160651-A | PHENYLPYRIDYLETHYLENE DERIVATIVE AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | IDEMITSU KOSAN CO LTD | 1986-03-28 | — | — | JP | disclosed |