SCHEMBL10824355

SCHEMBL10824355

NCCC(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NAALAD2 Q9Y3Q0 1/20 0.59
▸ ACE P12821 4/20 0.58
▸ FOLH1 Q04609 1/20 0.56
▸ MME P08473 1/20 0.56
▸ ITGB3 P05106 2/20 0.55
▸ ITGA2B P08514 2/20 0.55
▸ CHRND Q07001 6/20 0.54
▸ CHRNA1 P02708 2/20 0.54
▸ CHRNG P07510 2/20 0.54
▸ CHRNB1 P11230 2/20 0.54
▸ GRIA1 P42261 1/20 0.54
▸ CA1 P00915 1/20 0.53
▸ CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629789 1.00 NAALAD2 (0.59) NAALAD2ACEFOLH1MMEITGB3
SCHEMBL29885832 0.89 ACE (0.63) NAALAD2ACEMMEITGB3ITGA2B
SCHEMBL1330423 0.89 ACE (0.63) NAALAD2ACEMMEITGB3ITGA2B
SCHEMBL1330426 0.89 ACE (0.63) NAALAD2ACEMMEITGB3ITGA2B
SCHEMBL10338342 0.89 ITGB3 (0.66) ITGB3ITGA2BCHRNDCHRNA1CHRNG
SCHEMBL10338341 0.89 ITGB3 (0.66) ITGB3ITGA2BCHRNDCHRNA1CHRNG
SCHEMBL479126 0.88 ACE (0.60) NAALAD2ACEFOLH1MMEITGB3
SCHEMBL3459805 0.88 ACE (0.60) NAALAD2ACEFOLH1MMEITGB3
SCHEMBL7110125 0.88 ACE (0.60) NAALAD2ACEFOLH1MMEITGB3
SCHEMBL479125 0.88 ACE (0.60) NAALAD2ACEFOLH1MMEITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61063692-A — — None — — JP disclosed
US-12018049-B2 Compositions and related methods for controlling vector-borne diseases FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-25 — — US disclosed
US-20210360934-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-11-25 — — US disclosed
US-20210275635-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-09 — — US disclosed
US-20200261536-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING, INC. 2020-08-20 — — US disclosed
CN-111225686-A Treatment of inflammatory diseases using ingestible devices to release immunomodulators 普罗根尼蒂公司 2020-06-02 — — CN disclosed
US-20200060286-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-27 — — US disclosed
EP-3573638-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES Flagship Pioneering Innovations V, Inc. (US) 2019-12-04 — — EP disclosed
CN-110430801-A Treatment of gastrointestinal disorders using TNF inhibitors PROGENITY INC 2019-11-08 — — CN disclosed
CN-110402097-A Gastrointestinal tract detection method, device and system PROGENITY INC 2019-11-01 — — CN disclosed
CN-110167589-A Treatment of gastrointestinal disorders using integrin inhibitors 普罗根尼蒂公司 2019-08-23 — — CN disclosed
CN-110087530-A Gastrointestinal tract detection method, device and system 普罗根尼蒂公司 2019-08-02 — — CN disclosed
CN-110072519-A Treatment of gastrointestinal disorders using JAK inhibitors and devices 普罗根尼蒂公司 2019-07-30 — — CN disclosed
CN-110072551-A Treatment of gastrointestinal disorders using IL-12/IL-23 inhibitors released using ingestible devices 普罗根尼蒂公司 2019-07-30 — — CN disclosed
US-20190216093-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING, INC. 2019-07-18 — — US disclosed
WO-2018140507-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING, INC. (US) 2018-08-02 — — WO disclosed
WO-2018140518-A1 COMPOSITIONS AND RELATED METHODS FOR CONTROLLING VECTOR-BORNE DISEASES FLAGSHIP PIONEERING, INC. (US) 2018-08-02 — — WO disclosed
WO-2018140519-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING, INC. (US) 2018-08-02 — — WO disclosed
JP-S6163692-A NOVEL 2'-5' OLIGOADENYLIC ACID COMPOUND, PREPARATION THEREOF AND ANTIGEN FOR 125I-LABELING COMPOSED OF SAME USED FOR 2'5' OLIGOADENYLIC ACID MEASUREMENT BY RADIOIMMUNOASSAY SAWAI HIROAKI 1986-04-01 — — JP disclosed
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