SCHEMBL10824399

SCHEMBL10824399

CCOC(=O)N1CC=CC(=O)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MAPT P10636 5/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
MDM2 Q00987 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
POLB P06746 2/20 0.41
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
SETD7 Q8WTS6 1/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
GSK3A P49840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9184668 0.80 PSEN1 (0.59) ALDH1A1MEN1KMT2AMAPK1RAB9A
SCHEMBL31503973 0.77 TSHR (0.50) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL1250833 0.74 PSEN1 (0.31)
SCHEMBL31503999 0.71 GSK3A (0.44) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL8380828 0.71 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL30305960 0.70 TSHR (0.41) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL7394679 0.69 DPP4 (0.49) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL4283831 0.69
SCHEMBL9584501 0.68 TSHR (0.50) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL31739673 0.67 PSEN1 (0.55) ALDH1A1MAPTMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61057579-A None JP disclosed
JP-S6157579-A PREPARATION OF 3-AMINOPYRROLIDINE OR ITS SALT TOYAMA CHEM CO LTD 1986-03-24 JP disclosed
JP-S06157579-A 0001-01-01 JP disclosed