SCHEMBL10824601

SCHEMBL10824601

C=C1COC(C)(c2ccccc2C)O1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.33
OPRM1 P35372 1/20 0.32
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754471 0.76 CYP1A2 (0.35) OPRM1TSHR
SCHEMBL12681587 0.75 TSHR (0.38) HDAC4OPRM1TSHRACHE
SCHEMBL11134355 0.69 HDAC4 (0.37) HDAC4OPRM1
SCHEMBL30717248 0.69 TSHR (0.39) HDAC4OPRM1TSHRACHE
SCHEMBL13752017 0.64 AVPR1A (0.34)
SCHEMBL14232524 0.62 CYP3A4 (0.34) HDAC4OPRM1TSHRACHE
SCHEMBL13263313 0.62 HDAC4 (0.33) HDAC4OPRM1TSHRACHE
SCHEMBL18474031 0.60 AVPR1A (0.37) ACHE
SCHEMBL11800826 0.60 HDAC4 (0.50) HDAC4OPRM1TSHRACHE
SCHEMBL1979147 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61118379-A None JP disclosed
JP-S61118379-A POLYMERIZABLE MONOMER HAVING LOW SHRINKAGE HITACHI LTD 1986-06-05 JP disclosed