SCHEMBL11134355

SCHEMBL11134355

Cc1ccccc1C1(C)OC(=O)CC(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.37
TDP1 Q9NUW8 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALOX12 P18054 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8121004 0.83 HDAC4 (0.38) HDAC4TDP1NPSR1CYP1A2CYP3A4
SCHEMBL7789544 0.79 CYP2D6 (0.44) HDAC4MAPTALDH1A1LMNAPOLB
SCHEMBL3291202 0.75 SIRT1 (0.46) TDP1CYP1A2CYP2C9ALDH1A1POLB
SCHEMBL12681587 0.72 TSHR (0.38) HDAC4TDP1CYP3A4HTTALDH1A1
SCHEMBL11069958 0.69 CYP1A2 (0.39) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL7418804 0.68 SIGMAR1 (0.46) CYP1A2L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL30717248 0.66 TSHR (0.39) HDAC4TDP1CYP3A4ALDH1A1POLB
SCHEMBL8123326 0.66 CYP2D6 (0.45) HDAC4HTTMAPTALDH1A1LMNA
SCHEMBL8106520 0.65 OPRM1 (0.41) HDAC4TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL8121148 0.64 KMT2A (0.43) NPSR1HTTALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120201986-A Sun-proof cosmetic 株式会社高丝 2025-06-24 CN disclosed
CN-110997795-B High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2022-10-04 CN disclosed
CN-110799549-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2022-03-15 CN disclosed
CN-108473612-B Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2021-02-05 CN disclosed
CN-110997795-A High stiffness polypropylene impact copolymers 埃克森美孚化学专利公司 2020-04-10 CN disclosed
CN-110799549-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for propylene polymerization 东邦钛株式会社 2020-02-14 CN disclosed
US-4368241-A Alkoxysilanes and method for making GENERAL ELECTRIC COMPANY (US) 1983-01-11 US disclosed
US-4307240-A Alkoxysilanes and method for making GENERAL ELECTRIC COMPANY (US) 1981-12-22 US disclosed