Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.55 |
| ▸ | HPGD | P15428 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635675 | 0.80 | HSD17B10 (0.60) | HSD17B10HPGDTSHRCYP3A4HSP90AA1 | |
| SCHEMBL70334 | 0.77 | HSD17B10 (0.73) | HSD17B10HPGDTSHRCYP3A4HSP90AA1 | |
| SCHEMBL10938910 | 0.77 | AHR (0.41) | HSD17B10HPGDTSHRCYP3A4ALDH1A1 | |
| SCHEMBL29402084 | 0.77 | HSD17B10 (0.73) | HSD17B10HPGDTSHRCYP3A4HSP90AA1 | |
| SCHEMBL8538111 | 0.77 | HPGD (0.38) | HSD17B10HPGDTSHRCYP3A4ALDH1A1 | |
| SCHEMBL15149919 | 0.77 | HSD17B10 (0.48) | HSD17B10HPGDTSHRCYP3A4HSP90AA1 | |
| SCHEMBL10686717 | 0.74 | KDM4E (0.35) | HSD17B10HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL6513110 | 0.72 | — | — | |
| SCHEMBL8851340 | 0.72 | — | — | |
| SCHEMBL10826285 | 0.71 | RECQL (0.33) | HSD17B10HPGDCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617334-A | SYNERGISTIC MIXURE OF MERCAPTANS AND MERCAPTOANTIMONY COMPOUNDS; HEAT RESISTANCE; PIPES | MORTON THIOKOL, INC. (US) | 1986-10-14 | — | — | US | disclosed |
| US-4558083-A | MIXTURE OF ORGANOTIN COMPOUND AND AN ORTHO HYDROXYTHIOPHENBOLIC COMPOUND;HEAT RESISTANCE | MORTON THIOKOL, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0062406-B1 | POLYMER STABILISING COMPOSITIONS, POLYMERS STABILISED THEREWITH AND SHAPED ARTICLES FORMED FROM SUCH POLYMERS | MORTON THIOKOL, INC. (US) | 1985-06-05 | — | — | EP | disclosed |
| EP-0059610-B1 | STABILIZER COMPOSITIONS, HALOGEN-CONTAINING POLYMER COMPOSITIONS CONTAINING THE SAME AND SHAPED ARTICLES CONTAINING SAID POLYMER COMPOSITIONS | MORTON THIOKOL, INC. (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0134348-A1 | Halogen-containing polymers stabilized with organic antimony compound and an ortho mercapto phenol compound | MORTON THIOKOL, INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4440891-A | HEAT RESISTANCE | CARSTAB CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0062406-A1 | Polymer stabilising compositions, polymers stabilised therewith and shaped articles formed from such polymers | MORTON THIOKOL, INC. (US) | 1982-10-13 | — | — | EP | disclosed |
| EP-0059610-A1 | Stabilizer compositions, halogen-containing polymer compositions containing the same and shaped articles containing said polymer compositions | MORTON THIOKOL, INC. (US) | 1982-09-08 | — | — | EP | disclosed |
| US-4315850-A | HEAT RESISTANT PIPES | CARSTAB CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4314934-A | DISCOLORATION INHIBITION, HEAT RESISTANT | CARSTAB CORPORATION (US) | 1982-02-09 | — | — | US | disclosed |