Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TOP2A | P11388 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 6/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826117 | 1.00 | KDM4E (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826115 | 1.00 | KDM4E (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826833 | 1.00 | KDM4E (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10825853 | 1.00 | KDM4E (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826836 | 1.00 | KDM4E (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826118 | 0.99 | KDM4E (0.67) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826116 | 0.99 | KDM4E (0.67) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826185 | 0.95 | APP (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10826184 | 0.95 | APP (0.66) | KDM4ELMNATOP2AAPPALOX5 | |
| SCHEMBL10825843 | 0.91 | KDM4E (0.72) | KDM4ELMNAAPPAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618627-A | ALLERGIES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0125919-A2 | Catechol derivatives, their production and intermediates therefor, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |