Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018429 | 0.80 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL50085 | 0.78 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL2047245 | 0.78 | MAPT (0.48) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL29661990 | 0.78 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| Syringol SCHEMBL156388 | 0.78 | KDM4E (0.80) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL28559029 | 0.77 | MAPT (0.64) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| Syringol SCHEMBL7610366 | 0.76 | KDM4E (0.76) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| Syringol SCHEMBL8986496 | 0.76 | KDM4E (0.76) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| Syringol SCHEMBL6049240 | 0.76 | KDM4E (0.76) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL2200950 | 0.74 | CYP1A2 (0.48) | MAPTKDM4EALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177582-A1 | POLYPHENYLENE ETHER BLENDS CONTAINING ELECTROSTATICALLY BOUND ADDITIVE | GENERAL ELECTRIC COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |
| WO-1985004667-A1 | POLYPHENYLENE ETHER BLENDS CONTAINING ELECTROSTATICALLY BOUND ADDITIVE | GENERAL ELECTRIC COMPANY (US) | 1985-10-24 | — | — | WO | disclosed |