SCHEMBL10826348

SCHEMBL10826348

NCCS(=O)(=O)c1ccccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
CA2 P00918 4/20 0.54
CA9 Q16790 3/20 0.54
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA4 P22748 2/20 0.54
CYP2C9 P11712 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
KYNU Q16719 2/20 0.50
HTR6 P50406 1/20 0.48
TTR P02766 1/20 0.37
ALOX15 P16050 2/20 0.36
CASP1 P29466 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PLCG1 P19174 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4838314 0.87 PLCG1 (0.41) GAACA2CA9CA12CA1
SCHEMBL375690 0.82 GAA (0.54) GAACA2CA9CA12CA1
SCHEMBL9337554 0.82 GAA (0.54) GAACA2CA9CA12CA1
SCHEMBL635315 0.82 CA2 (0.57) GAACA2CA9CA12CA1
SCHEMBL231473 0.80 GAA (0.52) GAACA2CA9CA12CA1
Sulfuric Acid SCHEMBL27866658 0.79 CA2 (0.54) GAACA2CA9CA12CA1
SCHEMBL11320896 0.79 CA2 (0.53) GAACA2CA9CA12CA1
SCHEMBL1972988 0.78 GAA (0.60) GAACA2CA9CA12CA1
SCHEMBL7288933 0.78 GAA (0.60) GAACA2CA9CA12CA1
SCHEMBL10682818 0.78 KMT2A (0.44) GAACYP2C9HTR6ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0137417-B1 PROCESS FOR THE PREPARATION OF AMINOBENZENE-ALKYLSULFONES OR AMINOBENZENE-ALKYLSULFOXIDES BAYER AG (DE) 1986-11-05 EP disclosed
EP-0137417-A1 Process for the preparation of aminobenzene-alkylsulfones or aminobenzene-alkylsulfoxides BAYER AG (DE) 1985-04-17 EP disclosed
EP-0017883-B1 SULPHUR-CONTAINING DIISOCYANATES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS SYNTHESIS COMPONENTS TO PREPARE POLYURETHANES BAYER AG (DE) 1981-10-21 EP disclosed
EP-0017883-A1 Sulphur-containing diisocyanates, a process for their preparation and their use as synthesis components to prepare polyurethanes BAYER AG (DE) 1980-10-29 EP disclosed