SCHEMBL10828007

SCHEMBL10828007

CC/C(=C\C=O)COC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 2/20 0.34
FAAH O00519 1/20 0.34
PTPN1 P18031 1/20 0.33
GLO1 Q04760 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
PGR P06401 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
HTR1A P08908 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRM3 P20309 1/20 0.30
TBXA2R P21731 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10828010 1.00 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL9998249 0.80 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL9998251 0.80 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL9998524 0.77 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL9998523 0.77 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL10828247 0.76 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL10828246 0.76 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL2163122 0.74
SCHEMBL9997945 0.73 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL9997946 0.73 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0110309-B1 PROCESS FOR THE PREPARATION OF 1,4-DIACYLOXY-1,3-BUTADIENES BASF Aktiengesellschaft (DE) 1986-02-19 EP disclosed
EP-0110309-A1 Process for the preparation of 1,4-diacyloxy-1,3-butadienes BASF Aktiengesellschaft (DE) 1984-06-13 EP disclosed