Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829959 | 0.90 | KMT2A (0.37) | ALDH1A1PTGDR2KMT2AKDM4EPOLB | |
| SCHEMBL10830004 | 0.89 | PTGDR2 (0.35) | ALDH1A1PTGDR2PTGDRKMT2AKDM4E | |
| SCHEMBL3488954 | 0.86 | MAPT (0.36) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL638387 | 0.86 | MAPT (0.36) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL3490574 | 0.85 | FFAR4 (0.34) | ALDH1A1KMT2AKDM4EMDM2MAPK1 | |
| SCHEMBL636420 | 0.85 | FFAR4 (0.34) | ALDH1A1KMT2AKDM4EMDM2MAPK1 | |
| SCHEMBL638386 | 0.85 | MAPT (0.35) | ALDH1A1KMT2AKDM4EHTTPOLB | |
| SCHEMBL3488951 | 0.85 | MAPT (0.35) | ALDH1A1KMT2AKDM4EHTTPOLB | |
| SCHEMBL3490573 | 0.84 | MAPT (0.33) | KMT2AMAPK1 | |
| SCHEMBL636419 | 0.84 | MAPT (0.33) | KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4569938-A | Diuretic, antihypertensive and antihistaminic 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1986-02-11 | — | — | US | disclosed |