Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829959 | 0.90 | KMT2A (0.37) | PTGDR2CD69MAPTKMT2AALDH1A1 | |
| SCHEMBL10829680 | 0.89 | ALDH1A1 (0.37) | PTGDR2PTGDRPKMKMT2AALDH1A1 | |
| SCHEMBL10830719 | 0.78 | FFAR1 (0.33) | FFAR1PPARG | |
| SCHEMBL10829782 | 0.78 | CD69 (0.36) | PKMCD69MAPTKMT2AALDH1A1 | |
| SCHEMBL10830006 | 0.78 | HCAR2 (0.40) | PTGDR2ALOX5APFEN1PKMCD69 | |
| SCHEMBL3798183 | 0.77 | KDM4E (0.36) | KMT2AMEN1KDM4E | |
| SCHEMBL638387 | 0.75 | MAPT (0.36) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL3488954 | 0.75 | MAPT (0.36) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL3490574 | 0.74 | FFAR4 (0.34) | MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL636420 | 0.74 | FFAR4 (0.34) | MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4569938-A | Diuretic, antihypertensive and antihistaminic 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1986-02-11 | — | — | US | disclosed |