Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10830300 | 0.99 | ABCB1 (0.53) | ABCB1ATMMEN1KMT2APOLB | |
| SCHEMBL10830626 | 0.94 | ABCB1 (0.47) | ABCB1ATMMEN1KMT2APOLB | |
| SCHEMBL3396983 | 0.93 | ABCB1 (0.50) | ABCB1MEN1KMT2AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9735999 | 0.92 | MEN1 (0.51) | ABCB1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10829614 | 0.91 | ABCB1 (0.48) | ABCB1MEN1KMT2AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL10829914 | 0.90 | ABCB1 (0.47) | ABCB1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10830174 | 0.90 | MEN1 (0.47) | ABCB1MEN1KMT2APOLBADRB2 | |
| SCHEMBL10829647 | 0.90 | MEN1 (0.47) | ABCB1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10830785 | 0.89 | ATM (0.49) | ABCB1ATMMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL10829709 | 0.89 | MEN1 (0.47) | ABCB1MEN1KMT2APOLBADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571409-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-18 | — | — | US | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |