SCHEMBL3396983

SCHEMBL3396983

CCCNCC(O)COC(Cc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 11/20 0.50
ADRB2 P07550 3/20 0.50
ADRB1 P08588 3/20 0.50
ADRB3 P13945 3/20 0.50
LMNA P02545 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP3A4 P08684 2/20 0.50
KCNH2 Q12809 2/20 0.50
KCNK3 O14649 1/20 0.50
SLC22A1 O15245 1/20 0.50
ABCC9 O60706 1/20 0.50
KCNK2 O95069 1/20 0.50
ABCB11 O95342 1/20 0.50
ADRA2C P18825 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
SLC6A4 P31645 1/20 0.50
ADRA1A P35348 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9735999 0.99 MEN1 (0.51) ABCB1ADRB2ADRB1ADRB3LMNA
SCHEMBL10829614 0.93 ABCB1 (0.48) ABCB1ADRB2ADRB1ADRB3LMNA
SCHEMBL10829713 0.93 ABCB1 (0.53) ABCB1ADRB2ADRB1ADRB3LMNA
SCHEMBL10829647 0.92 MEN1 (0.47) ABCB1ADRB2ADRB1ADRB3LMNA
SCHEMBL10830174 0.92 MEN1 (0.47) ABCB1ADRB2ADRB1ADRB3LMNA
Hydrochloric Acid SCHEMBL10830300 0.92 ABCB1 (0.53) ABCB1ADRB2ADRB1ADRB3LMNA
Hydrochloric Acid SCHEMBL10829914 0.92 ABCB1 (0.47) ABCB1ADRB2ADRB1ADRB3LMNA
SCHEMBL9737421 0.92 ABCB1 (0.45) ABCB1ADRB2ADRB1ADRB3LMNA
Hydrochloric Acid SCHEMBL10830211 0.91 MEN1 (0.46) ABCB1ADRB2ADRB1ADRB3LMNA
Hydrochloric Acid SCHEMBL10829709 0.91 MEN1 (0.47) ABCB1ADRB2ADRB1ADRB3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160229914-A1 METHOD OF TREATING A PATHOLOGICAL SYNDROME EPSHTEIN OLEG ILIICH (RU) 2016-08-11 US disclosed
US-20160137750-A1 METHOD OF TREATING A PATHOLOGICAL SYNDROME EPSHTEIN OLEG IIIICH (RU) 2016-05-19 US disclosed
US-9303091-B2 Method of treating disorders of the cardiovascular system and a pharmaceutical agent Epshtein, Oleg Iliich (RU) 2016-04-05 US disclosed
US-9273117-B2 Method for administering homeopathically potentized antibody OLEG ILIICH EPSHTEIN (RU) 2016-03-01 US disclosed
US-9228024-B2 Method of treating hypertension disorder and a pharmaceutical agent EPSHTEIN, OLEG I. (RU) 2016-01-05 US disclosed
US-20140056923-A9 METHOD OF TREATING HYPERTENSION DISORDER AND A PHARMACEUTICAL AGENT EPSHTEIN, OLEG I. (RU) 2014-02-27 US disclosed
US-8535664-B2 Administration of an activated form of ultra-low doses of antibodies to an antigen, obtained using homeopathic techniques; drug dependence/drug withdrawal; side effect reduction Epshtein, Oleg I. (RU) 2013-09-17 US disclosed
US-7815904-B2 Method of treating a pathological syndrome and a pharmaceutical agent Epshtein, Oleg Iliich (RU) 2010-10-19 US disclosed
US-20100239569-A1 Method Of Treating Disorders Of The Cardiovascular System And A Pharmaceutical Agent OLEG ILIICH EPSHTEIN (RU) 2010-09-23 US disclosed
US-20100166762-A1 METHOD OF TREATING A PATHOLOGICAL SYNDROME Epshtein, Oleg Iliich (RU) 2010-07-01 US disclosed
US-20080019982-A1 Method of treating a pathological syndrome and a pharmaceutical agent EPSHTEIN, OLEG I. (RU) 2008-01-24 US disclosed
US-20070224187-A1 Method of treating a pathological syndrome and a pharmaceutical agent EPSHTEIN, OLEG I. (RU) 2007-09-27 US disclosed
US-20030099636-A1 Curing method for pathologic syndrome and medicinal preparation EPSHTEIN, OLEG I. (RU) 2003-05-29 US disclosed
EP-1295606-A1 CURING METHOD FOR PATHOLOGIC SYNDROME AND A MEDICINAL PREPARATION Epshtein, Oleg Iliich (RU) 2003-03-26 EP disclosed
EP-0462150-B1 NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM LAEVOSAN GMBH & CO KG (AT) 1994-09-07 EP disclosed
US-5334602-A Antiarrhytmic agent LAEVOSAN-GESELLSCHAFT GMBH (AT) 1994-08-02 US disclosed
US-5118685-A Antiarrhythmia agents BASF AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
EP-0152556-B1 AMINOPROPANOL DERIVATIVES OF SUBSTITUTED 2-HYDROXY-PROPIOPHENONES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1987-01-21 EP disclosed
US-4612320-A Aminopropanol derivatives of 1-(2-hydroxyphenyl)-3-phenylpropanols and therapeutic agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1986-09-16 US disclosed
EP-0152556-A1 Aminopropanol derivatives of substituted 2-hydroxy-propiophenones, process for their preparation and therapeutic agents containing them BASF Aktiengesellschaft (DE) 1985-08-28 EP disclosed