Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463315 | 0.85 | KMT2A (0.50) | HTTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL16815732 | 0.85 | KMT2A (0.50) | HTTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL8953561 | 0.85 | KMT2A (0.50) | HTTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL7516087 | 0.85 | KMT2A (0.50) | HTTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL28019826 | 0.81 | HPGD (0.50) | HTTPOLBNPSR1MEN1KMT2A | |
| SCHEMBL18342037 | 0.78 | CYP1A2 (0.48) | HTTPOLBMEN1KMT2AHPGD | |
| SCHEMBL28584327 | 0.78 | CYP1A2 (0.48) | HTTPOLBMEN1KMT2AHPGD | |
| SCHEMBL28582434 | 0.78 | CYP1A2 (0.48) | HTTPOLBMEN1KMT2AHPGD | |
| SCHEMBL10829626 | 0.78 | LDHA (0.61) | HTTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7385695 | 0.77 | CYP1A2 (0.59) | HTTMEN1KMT2ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571409-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-18 | — | — | US | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |