SCHEMBL10830364

SCHEMBL10830364

CC/C=C\CCC1C(=O)C=CC1OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 3/20 0.32
CYP19A1 P11511 2/20 0.32
RXRA P19793 2/20 0.32
OXER1 Q8TDS5 2/20 0.32
FFAR1 O14842 1/20 0.32
MAPT P10636 1/20 0.32
TRPA1 O75762 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
NR4A1 P22736 1/20 0.32
PTPN7 P35236 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
PTGS1 P23219 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10712590 0.86 AKR1C4 (0.37) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10712291 0.86 AKR1C4 (0.37) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10831038 0.85 PPARG (0.46) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10717059 0.83 PPARG (0.37) PPARGPPARDPPARA
SCHEMBL10830934 0.82 PPARG (0.39) PPARGPPARDPPARAMAPTPOLB
SCHEMBL10715509 0.80 PPARG (0.53) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10629085 0.78 PPARG (0.59) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10631183 0.77 ALDH1A1 (0.34) PPARGPPARDPPARAALDH1A1CYP19A1
SCHEMBL10713033 0.77 PPARG (0.61) PPARGPPARDPPARAALDH1A1MAPT
SCHEMBL10714235 0.77 PPARG (0.61) PPARGPPARDPPARAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4608442-A TREATMENT OF CORRESPONDING 2-ACYLOXY-4- CYCLOPENTENONES WITH ACID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-26 US disclosed
EP-0133251-A2 Process for preparing 4-hydroxy-2-cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-02-20 EP disclosed